Caffeine Lactose : Fakta atau Mitos
Caffeine is a stimulant found naturally in beverages like coffee and tea. It’s also added to others, such as energy drinks and soda.
Caffeine increases chemicals in your brain that improve mood, combat fatigue and enhance focus.
For this reason, many people turn to their caffeine-containing beverage of choice to get their day started or pick themselves up from a mid-afternoon crash.
However, it’s thought that caffeine’s stimulating effects become less noticeable over time because your body becomes tolerant or less responsive to its effects.
This article explains how caffeine produces its stimulating effects and whether it’s possible to develop a caffeine tolerance.
Caffeine mainly works by blocking your brain’s adenosine receptors, which play a role in sleep, arousal, and cognition (1 ).
A molecule called adenosine usually binds to these receptors, inhibiting the release of brain chemicals like dopamine that increase arousal and promote wakefulness (2 ).
By blocking adenosine from binding to its receptor, caffeine increases the release of these stimulating brain chemicals that decrease fatigue and increase alertness (3 , 4 ).
One study showed that a high caffeine dose can block up to 50% of adenosine receptors in the brain (5 ).
The stimulating effects of caffeine occur within 30–60 minutes of consuming the substance and last for 3–5 hours, on average (3 , 6 ).
However, according to a seminal study from the 1980s, regularly consuming caffeine increases your body’s production of adenosine receptors and therefore the likelihood of adenosine binding to those receptors (7 ).
Consequently, this decreases caffeine’s effects, causing you to become tolerant over time (7 ).
SUMMARYCaffeine increases alertness and decreases fatigue by blocking adenosine from binding to its receptor. Regularly consuming caffeine increases the number of adenosine receptors, decreasing caffeine’s effects.
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